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CFTM 633 maleimide

品牌
Sigma-Aldrich
货号
SCJ4600038
规格纯度
suitable for fluorescence
参考价格
4603.88 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Far-red fluorescent dyes offer the advantage of ultra sensitive detection because background signal due to autofluorescence in most biological samples is minimal in this spectral region. For many years, the cyanine dye Cy®5 has been the dye of choice for such detection. More recently, Alexa Fluor® 647 has been developed as a better alternative by having brighter fluorescence and higher photostability. Despite the improvement, Alexa Fluor® 647 still lacks sufficient photostability required for many demanding applications. On the other hand, while Alexa Fluor® 633 is photostable, its fluorescence on proteins is very weak. In fact, it has been a challenging task for dye chemists to develop a far-red fluorescent dye that is both highly fluorescent and photostable for protein and nucleic acid labeling. Using new chemistry, scientists at Biotium have successfully developed a series of far-red and near-IR dyes to overcome these challenges. With its absorption peak at 630 nm, CF633 can be optimally excited by the 633 nm He-Ne laser or the 635 nm red diode laser with emission maximum at 650 nm. Despite its shorter emission wavelength, which often is not favored by a Cy®5-based detection window on most instruments, CF633 is still significantly brighter than Alexa Fluor® 647. However, for detections using non-laser-based excitation and a Cy®5 filter set, the full advantage of CF633 will not be realized. In this case, we recommend CF640R, another outstanding far-red CF dye that is spectrally closer to Cy®5 or other similar cyanine-based dyes. The most important advantage of CF633 and other rhodamine-based far-red CF dyes are their unmatched photostability. The combination of superior brightness and photostability makes far-red CF dyes ideal choices for detections in the long wavelength region on a variety of instruments.

特点和优势

1. Yields the brightest anibody conjugates among spectrally similar dyes when excited by the 633 nm He-Ne laser or the 635 nm red diode laser. 2. Far more photostable than Alexa Fluor®647. 3. Highly water-soluble.

制备说明

Protect from light

法律信息

This product is distributed by sigma-aldrich Co. under the authorization of Biotium, Inc. This product is covered by one or more US patents and corresponding patent claims outside the US patents or pending applications owned or licensed by Biotium, Inc. including without limitation: 12/334,387; 12/607,915; 12/699,778; 12/850,578; 61/454,484. In consideration of the purchase price paid by the buyer, the buyer is hereby granted a limited, non-exclusive, non-transferable license to use only the purchased amount of the product solely for the buyer′s own internal research in a manner consistent with the accompanying product literature. Except as expressly granted herein, the sale of this product does not grant to or convey upon the buyer any license, expressly, by implication or estoppel, under any patent right or other intellectual property right of Biotium, Inc. Buyer shall not resell or transfer this product to any third party, or use the product for any commercial purposes, including without limitation, any diagnostic, therapeutic or prophylactic uses. This product is for research use only. Any other uses, including diagnostic uses, require a separate license from Biotium, Inc. For information on purchasing a license to use this product for purposes other than research, contact Biotium, Inc., 3159 Corporate Place, Hayward, CA 94545, Tel: (510) 265-1027. Fax: (510) 265-1352. Email: btinfo@biotium.com.
ALEXA FLUOR is a registered trademark of Life Technologies
CF is a trademark of Biotium, Inc.
Cy is a registered trademark of Cytiva

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平100
形式solid
分子量 ~945 g/mol
ε (extinction coefficient)100000 at 630 nm
吸光度比值A280/630 nm 0.48
荧光λex 633 or 635 nm (Flow cytometry laser line)
λex 633 or 635 nm (Microscopy laser line)
λex 630 nm; λem 650 nm
适用性suitable for fluorescence
运输wet ice
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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