产品说明
应用
Chaetoglobosin A has been used as a standard for the detection and quantification of chaetoglobosin A from Chaetomium globosum by HPLC.
生化/生理作用
Chaetomium globosum is a fungus commonly found in water-damaged walls and causes Sick Building Syndrome (SBS). Chaetoglobosin A is a mycotoxic cytochalasin. Over 40 chaetoglobosins were characterized, many of which show acute toxicity to mammals, as well as cytotoxicity to human cancer cell lines such as KB, K562, MCF-7, and HepG2.
Cytochalasins were also found to inhibit glucose transport in human erythrocytes by binding to the glucose carrier on the erythrocyte membrane. Chaetoglobosin A was found to inhibit nematode proliferation and egg hatching. It also causes mortality of second stage juveniles of Meloidogyne incognita.
其他说明
Store the product sealed at −20 ℃. Under these conditions the product is stable for at least 2 years.
基本信息
| 经验(实验)分子式 | C32H36N2O5 |
| 分子量 | 528.64 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 生物来源 | Chaetomium globosum |
| 测定 | ≥98% (HPLC) |
| 溶解性 | DMSO: soluble 10 mg/mL methanol: soluble 10 mg/mL |
| 储存温度 | −20℃ |
| InChI | 1S/C32H36N2O5/c1-17-8-7-10-22-29-31(4,39-29)19(3)27-24(15-20-16-33-23-11-6-5-9-21(20)23)34-30(38)32(22,27)26(36)13-12-25(35)28(37)18(2)14-17/h5-7,9-14,16-17,19,22,24,27-29,33,37H,8,15H2,1-4H3,(H,34,38)/b10-7+,13-12+,18-14+/t17-,19-,22?,24-,27-,28+,29-,31+,32+/m0/s1 |
| InChI key | OUMWCYMRLMEZJH-VIRVUJSBSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
