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Anti-Human IgG (Fc specific)-Peroxidase antibody, Mouse monoclonal

品牌
Sigma-Aldrich
货号
SAB4200790
规格纯度
clone GG-7, purified from hybridoma cell culture
参考价格
5753.84 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

IgGs are the most common Immunoglobulins isotype in blood, lymph fluid, cerebrospinal fluid, and peritoneal fluid and a key players in the humoral immune response. IgGs include four subclasses (IgG1, IgG2, IgG3, and IgG4), they consist of a variable Fab fragment (which includes the antibody recognition site), and a conserved Fc fragment. The IgG subclasses differ in their physical and chemical properties, their distribution pattern is found to be age-dependent and every subclass has a specific biological function. IgG deficiencies are often associated with various diseases.
The Fc fragment has various important functions such as complement fixation, site for rheumatoid factor (autoantibody directed to Fc) attachment, passage through the placental membrane and protein A binding. A certain population of lymphocytes also possess an "Fc receptor". These functions indicate the importance of immunoreagents specific for the Fc fragment of Human IgG.
Monoclonal Anti-Human IgG (Fc specific) is specific for the Fc fragment of Human IgG and is observed with all human IgG subclasses but not with the Fab fragment of human IgG, purified light chains, human IgA or human IgM.

免疫原

Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads.

应用

The antibody is recommended to use in various immunological techniques, including ELISA.

外形

Supplied as a lyophilized powder

其他说明

This product is for R&D use only, not for drug, household, or other uses.

基本信息

NACRESNA.46

产品性质

质量水平200
生物来源mouse
偶联物peroxidase conjugate
抗体形式purified from hybridoma cell culture
antibody product typeprimary antibodies
克隆GG-7, monoclonal
形式lyophilized powder
species reactivityhuman
technique(s)direct ELISA: 1:40,000-1:80,000 using 2.5 μg/mL human IgG1 for coating
同位素/亚型IgG1
运输dry ice
储存温度−20℃

安全信息

象形图GHS07
警示用语:Warning
危险声明H317
预防措施声明P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
危险分类Skin Sens. 1
储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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