产品说明
一般描述
Tau (τ), also known as MAPT (microtubule associated protein tau) is encoded by the gene mapped on human chromosome 17q21.3. It is highly expressed in neurons but is most prominent in axons.
免疫原
chemically synthesized phosphopeptide derived from the region of human tau that contains serine262.
生化/生理作用
Removal of Tau (τ) results in developmental delay and learning disability. It participates in the pathology of Alzheimer′s disease (AD). Tau helps in the assembly and maintenance of microtubule structure. Measurement of phosphorylated tau (P-tau) levels in cerebrospinal fluid (CSF) acts a potential marker for differentiation between AD and dementia with Lewy bodies (DLB).
外形
Supplied in 100 μL of Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, with 50% glycerol, 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD03455773 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous glycerol solution |
| species reactivity | human, mouse, rat |
| technique(s) | western blot: 1:1,000 |
| UniProt登记号 | P10636 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MAPT(4137) mouse ... Mapt(17762) rat ... Mapt(29477) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
