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A71915 trifluoroacetate

(Arg6, β-cyclohexyl-Ala8, D-Tic16, Arg17, Cys18)-Atrial Natriuretic Factor (6-18) amide (Cys7→Cys18 disulfide), TFA salt

品牌
Sigma-Aldrich
CAS
132956-87-7
货号
SML2908
包装型号
规格纯度
≥95% (HPLC)
参考价格
1677 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

A71915 is a potent atrial natriuretic peptide A (ANP, NPPA) receptor (NPR1, ANP-A, ANPR-A, NPR-A) antagonist (pKi = 9.18 (Ki = 650 nM) by competitive binding against 300 nM rat ANP1-28 to human neuroblastoma NB-OK-1 cells; pA2 = 9.45 against rat ANP-induced cGMP production in NB-OK-1 cells). A71915 is reactive toward dog, human, mouse, rabbit, and rat species, and commonly employed both in cultures (1-10 μM) and in vivo for studying NPR-A-mediated responses.

基本信息

经验(实验)分子式C69H116N26O15S2 · xC2HF3O2
分子量1613.95 (free base basis)

产品性质

质量水平100
测定≥95% (HPLC)
形式powder
颜色 white to off-white
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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