产品说明
一般描述
A cell-permeable, N-myristoylated G-Protein Binding Peptide (mSIRK) that contains a single point mutation (Leu9 to Ala). In contrast to mSIRK (Cat. No. 371818), the mutant peptide is unable to enhance ERK1/2 phosphorylation. Useful as a negative control for mSIRK.
A cell-permeable, single point mutated (Leu9 to Ala), N-myristoylated G-protein βγ Binding Peptide (mSIRK). Does not enhance ERK1/2 phosphorylation and serves as a negative control for studies involving mSIRK (Cat. No. 371818).
包装
1 mg in Glass bottle
Packaged under inert gas
生化/生理作用
Product does not compete with ATP.
Cell permeable: yes
Primary Target
G-protein βγ
Reversible: no
警告
Toxicity: Standard Handling (A)
序列
Myr-N-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Ala-Gly-Tyr-Pro-Asp-Tyr-Asp-OH
外形
Supplied as a trifluoroacetate salt.
重悬
Following reconstitution aliquot and freeze(-20°C). Stock solutions are stable for up to 4 months at -20°C.
其他说明
Goubaeva, F., et al. 2003. J. Biol. Chem.278, 19634.
Scott, J.K., et al. 2001. EMBO J.20, 767.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C90H144N20O25 |
| 分子量 | 1906.23 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | lyophilized solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated (hygroscopic) |
| 颜色 | white |
| 溶解性 | DMSO: 5 mg/mL |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
