产品说明
一般描述
A potent, cell-permeable and irreversible inhibitor of calpain II (k2 = 28,900 M-1s-1). Also acts as an inhibitor of cathepsin L (k2 = 680,000 M-1s-1).
A potent, cell-permeable, and irreversible inhibitor of calpain II (k2 = 28,900 M-1s-1). Also acts as an inhibitor of cathepsin L (k2 = 680,000 M-1s-1).
包装
1 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Cell permeable: yes
k₂ = 28,900 M⁻¹s⁻¹ in the inhibition of calpain II; k2 = 680,000 M⁻¹s⁻¹ in the inhibition of cathepsin L
Reversible: no
Primary Target
calpain 2
警告
Toxicity: Standard Handling (A)
序列
Z-Leu-Leu-Tyr-CH₂F
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
分析说明
single spot by TLC
其他说明
Dutt, P., et al. 1998. FEBS Lett. 436, 367.
Angliker, H., et al. 1992. J. Med. Chem. 35, 216.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C30H40FN3O6 |
分子量 | 557.65 |
产品性质
质量水平 | 100 |
形式 | solid |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze desiccated |
颜色 | white to pale yellow |
溶解性 | DMSO: 25 mg/mL |
运输 | ambient |
储存温度 | −20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |