产品说明
一般描述
A specific, reversible, and substrate competitive inhibitor of PKG (Ki = 86 µM) relative to PKA (Ki = 550 µM). Sequence corresponds to a non-phosphorylatable analog (Ser32 to Ala32) of histone H2B (amino acids 29-35).
A more specific, reversible, and substrate competitive inhibitor of protein kinase G (Ki = 86 µM) relative to protein kinase A (Ki = 550 µM). Sequence corresponds to a non-phosphorylatable analog (Ser32 to Ala32) of histone H2B (amino acids 29-35).
包装
1 mg in Plastic ampoule
Yes
生化/生理作用
Target Ki: 86 µM against protein kinase G
Product does not compete with ATP.
Cell permeable: no
Reversible: yes
警告
Toxicity: Standard Handling (A)
序列
H-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH
其他说明
Glass, D.B., et al. 1983. Biochem. J.213, 159.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C38H74N18O10 |
| 分子量 | 943.11 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | lyophilized |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated (hygroscopic) |
| 溶解性 | water: 1 mg/mL |
| 运输 | ambient |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
