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Cathepsin L Inhibitor IV-Calbiochem

品牌
Sigma-Aldrich
货号
219433
规格纯度
The Cathepsin L Inhibitor IV controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
参考价格
1954.93 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

A potent, cell-permeable, selective, and reversible inhibitor of cathepsin L (IC50 = 1.9 nM). Inhibits the release of Ca2+ and hydroxyproline from bone in a bone culture system and prevents bone loss in ovariectomized mice (~50 mg/kg).
A potent, cell-permeable, selective, and reversible inhibitor of cathepsin L (IC50 = 1.9 nM). Also inhibits the release of Ca2+ and hydroxyproline from bone in an in vitro bone culture system and prevents bone loss in ovariectomized mice (~50 mg/kg).

包装

1 mg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Target IC50: 1.9 nM against Cathepsin L
Product does not compete with ATP.
Primary Target
cathepsin L
Reversible: yes

警告

Toxicity: Standard Handling (A)

序列

1-Naphthalenesulfonyl-Ile-Trp-CHO

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Yasuma, T., et al. 1998. J. Med. Chem. 41, 4301.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C27H29N3O4S
分子量491.60

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 white to off-white
溶解性DMSO: 5 mg/mL
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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