产品说明
一般描述
Anti-CK 5 & 6 positivity is seen in 65% to 100% of epithelioid mesotheliomas, in 0% to 19% of lung adenocarcinomas, and in 22% to 80% of serous carcinoma of the ovary and peritoneum. Keratin 5 & 6 expression in lung adenocarcinoma is not common, and when it occurs, the reaction is usually confined to small focal areas or scattered cells. The most probable cause of this finding is the presence of squamous differentiation of lung adenocarcinoma. Anti-CK 5 & 6 positivity has been useful in recognizing squamous cell carcinoma of the skin. Less than 10% of carcinomas of the breast, colon, and prostate stain positively for this marker. Anti-CK 5 & 6 has also been used successfully as a myoepithelial cell marker in the prostate and breast to determine malignancy. Anti-CK 5 & 6 is a useful marker to distinguish lung squamous cell carcinoma from lung adenocarcinoma and large cell carcinoma within a panel including antibodies against TTF-1, Napsin A, p63, SOX-2, desmocollin3, and desmoglein3.
质量
IVD | IVD | IVD | RUO |
联系
Cytokeratin 5 & 6 Positive Control Slides, Product No. 356S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
基本信息
NACRES | NA.41 |
产品性质
质量水平 | 500 100 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | diluted ascites fluid |
antibody product type | primary antibodies |
克隆 | D5 & 16B4, monoclonal |
描述 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
形式 | buffered aqueous solution |
species reactivity | human |
包装 | vial of 0.1 mL concentrate (356M-14) vial of 0.5 mL concentrate (356M-15) bottle of 1.0 mL predilute (356M-17) vial of 1.0 mL concentrate (356M-16) bottle of 7.0 mL predilute (356M-18) |
manufacturer/tradename | Cell Marque™ |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 |
同位素/亚型 | IgG1 |
控制 | mesothelioma |
运输 | wet ice |
储存温度 | 2-8℃ |
可视化 | cytoplasmic |