产品说明
一般描述
Programmed death-1 (PD-1) is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PD-1 is expressed by few B-cells, so anti-PD-1 may be a more specific and useful marker in the identification of angioimmunoblastic lymphoma. In addition, PD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells. PD-1 expression in angioimmunoblastic lymphoma lends further support to this model of T-cell oncogenesis, in which specific subtypes of T-cells may undergo neoplastic transformation and result in specific distinct histologic, immunophenotypic, and clinical subtypes of T-cell neoplasia.
质量
United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO
联系
PD-1 Positive Control Slides, Product No. 315S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Predilute: diluted in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Concentrate: diluted in Phosphate Buffered Saline, pH 7.2, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.
Download the latest released IFU
Note: This IFU may not apply to your specific product lot.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
产品性质
| 质量水平 | 500 100 |
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | EP239, monoclonal |
| 描述 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 包装 | vial of 0.1 mL concentrate (315R-14) vial of 0.1 mL concentrate Research Use Only (315R-14-RUO) vial of 0.5 mL concentrate (315R-15) vial of 1.0 mL concentrate (315R-16) vial of 1.0 mL concentrate Research Use Only (315R-16-RUO) vial of 1.0 mL pre-dilute Research Use Only (315R-17-RUO) vial of 1.0 mL predilute ready-to-use (315R-17) vial of 7.0 mL pre-dilute ready-to-use Research Use Only (315R-18-RUO) vial of 7.0 mL predilute ready-to-use (315R-18) |
| manufacturer/tradename | Cell Marque™ |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated) |
| 同位素/亚型 | IgG |
| 控制 | lymph node, tonsil |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| 可视化 | cytoplasmic, membranous |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
