产品说明
一般描述
CD35 (complement receptor 1) is a cell membrane-bound, monomeric glycoprotein found on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.
质量
United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO
联系
CD35 Positive Control Slides, Product No. 135S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
产品性质
| 质量水平 | 500 100 |
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | EP197, monoclonal |
| 描述 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 包装 | vial of 0.1 mL concentrate (135R-14) vial of 0.1 mL concentrate Research Use Only (135R-14-RUO) vial of 0.5 mL concentrate (135R-15) vial of 1.0 mL concentrate (135R-16) vial of 1.0 mL concentrate Research Use Only (135R-16-RUO) vial of 1.0 mL pre-dilute Research Use Only (135R-17-RUO) vial of 1.0 mL predilute ready-to-use (135R-17) vial of 7.0 mL pre-dilute ready-to-use Research Use Only (135R-18-RUO) vial of 7.0 mL predilute ready-to-use (135R-18) |
| manufacturer/tradename | Cell Marque™ |
| 浓度 | 0.1-5.0 μg/mL (predilute) 2.5-125 μg/mL (concentrate) |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated) |
| 同位素/亚型 | IgG |
| 控制 | tonsil |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| 可视化 | membranous |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
