产品说明
一般描述
CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Anti-CD14 antibody labels Kupffer cells in liver sinusoids. In lymphoid tissues, dendritic cells are distinctly stained. Most other normal tissues are negative. This antibody labels monocyte-macrophages and Langerhans cells in Langerhans cell histiocytosis. Tumor cells are positive in monocytic leukemia and true histiocytic lymphomas for CD14. Sinusoidal histiocytes express CD14 and CD 169, whereas most of the other monocyte-derived cells in reactive lymph node lack these markers. Anti-CD14 labels numerous diffuse large B-cell lymphomas and splenic marginal zone lymphoma but not in other B-cell lymphomas.
质量
IVD | IVD | IVD | RUO |
联系
CD14 Positive Control Slides, Product No. 114S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 500 100 |
偶联物 | unconjugated |
抗体形式 | culture supernatant |
antibody product type | primary antibodies |
克隆 | EPR3653, monoclonal |
描述 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
形式 | buffered aqueous solution |
species reactivity | human |
包装 | vial of 0.1 mL concentrate (114R-14) vial of 0.5 mL concentrate (114R-15) bottle of 1.0 mL predilute (114R-17) vial of 1.0 mL concentrate (114R-16) bottle of 7.0 mL predilute (114R-18) |
manufacturer/tradename | Cell Marque™ |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 |
同位素/亚型 | IgG |
控制 | tonsil |
运输 | wet ice |
储存温度 | 2-8℃ |
可视化 | cytoplasmic, membranous |