产品说明
一般描述
Calretinin is a 29 kDa calcium-binding protein thought to play a role in the cell cycle. Anti-calretinin has been shown to be useful in differentiating mesothelioma from adenocarcinomas from the lung and other sources. The sensitivity of anti-calretinin in distinguishing reactive mesothelial cells from adenocarcinoma cells is 100%, and the specificity is up to 80%. Light, focal, cytoplasmic staining of adenocarcinoma cells may be seen in 10 to 30% of cases. Anti-calretinin has also demonstrated utility in differentiating adrenal cortical neoplasms (+) from pheochromocytomas (-). Calretinin has also been useful in diagnosing granulosa cell tumor of the ovary amongst its mimics. Other ovarian tumors that stain with calretinin are Sertoli-Leydig cell tumor, Sertoli cell tumor, Leydig cell tumor, and sex cord tumor with annular tubules, as well as steroid cell tumor.9
联系
Calretinin Positive Control Slides, Product No. 232S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 500 100 |
| 偶联物 | unconjugated |
| 抗体形式 | culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | SP13, monoclonal |
| 描述 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 包装 | vial of 0.1 mL concentrate (232R-14) vial of 0.5 mL concentrate (232R-15) bottle of 1.0 mL predilute (232R-17) vial of 1.0 mL concentrate (232R-16) bottle of 7.0 mL predilute (232R-18) |
| manufacturer/tradename | Cell Marque™ |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 |
| 同位素/亚型 | IgG1 |
| 控制 | mesothelioma |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| 可视化 | cytoplasmic, nuclear |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
