产品说明
一般描述
Beta-Catenin is a 92 kD protein normally found in the cytoplasm of the cell in the submembranous location. This protein is associated with E-Cadherin and may be essential for the function of E-Cadherin. Mutations in the Beta-Catenin gene result in nuclear accumulation of this protein. Nuclear accumulation of this protein has been demonstrated in fibromatosis lesions of the breast and abdomen and therefore is useful in differentiating this lesion from other spindle cell lesions that may occur in these locations. Nuclear accumulation of Beta-Catenin has also been demonstrated in colorectal carcinoma.
质量
 IVD |  IVD |  IVD |  RUO |
联系
Beta-Catenin Positive Control Slides, Product No. 224S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.
Download the latest released IFU
Note: This IFU may not apply to your specific product lot.
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 500 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | 14, monoclonal |
| 描述 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 包装 | vial of 0.1 mL concentrate (224M-14) vial of 0.5 mL concentrate (224M-15) bottle of 1.0 mL predilute (224M-17) vial of 1.0 mL concentrate (224M-16) bottle of 7.0 mL predilute (224M-18) |
| manufacturer/tradename | Cell Marque™ |
| 浓度 | 1.0-5.0 μg/mL (predilute) 25-125 μg/mL (concentrate) |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 |
| 同位素/亚型 | IgG1 |
| 控制 | fibromatosis of breast |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| 可视化 | membranous, nuclear |
