应用
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.
备注
Store in a cool place. Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.
基本信息
MDL
MFCD00008028
EINECS
205-630-1
分子式
ICH2CONH2
分子量
184.96
熔点
92-95°(dried)
灵敏度
Keep Cold. Light Sensitive.
形态
Crystalline solid
溶解性
Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.
Beilstein
1739080
GHS危害和防范说明
GHS符号
Hazard Statements
H301-H315-H319-H317-H335
Toxic if swallowed.Causes skin irritation.Causes serious eye irritation.May cause an allergic skin reaction.May cause respiratory irritation.
Precautionary Statements
P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
6.1
包装组
III
危险类别
25-36/37/38-43
Toxic if swallowed.Irritating to eyes, respiratory system and skin.May cause sensitization by skin contact.
安全等级
24-26-37-45
Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
RTECS
AC4200000
TSCA
是
