应用
tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.
备注
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
基本信息
MDL
MFCD00007593
EINECS
212-795-3
分子式
C5H12N2O2
分子量
132.16
熔点
37-41°
沸点
63-65°/0.1mm
闪点
91°(195°F)
灵敏度
Keep Cold. Moisture Sensitive.
形态
Crystalline powder
溶解性
Soluble in ethanol and methanol.
Beilstein
1756967
GHS危害和防范说明
GHS符号
Hazard Statements
H228
Flammable solid.
Precautionary Statements
P210-P280-P240-P241-P370+P378a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Wear protective gloves/protective clothing/eye protection/face protection.Ground/bond container and receiving equipment.Use explosion-proof electrical/ventilating/lighting/ equipment.In case of fire: Use for extinction: CO2, powder or water spray.
安全信息
危险等级
4.1
包装组
II
危险类别
11
Highly flammable.
安全等级
33
Take precautionary measures against static discharges.
欧盟危险品标志
TSCA
是