应用
2,2,2-Trichloroethyl chloroformate is used as a protecting reagent for aliphatic and aromatic hydroxyl and amino groups. It is used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples, during N-demethylation of dextromethorphan. It was used as starting reagent during the synthesis of 6-Nor-9,10-dihydrolysergic acid methyl ester.

备注
Moisture Sensitive. Desiccate at 4?°C. Store under inert gas. Incompatible materials are Strong oxidizing agents.

基本信息

MDL
MFCD00000810

EINECS
241-363-7

分子式
ClCO₂CH₂CCl₃

分子量
211.86

熔点
0-2°

沸点
171-172°

闪点
>100°(212°F)

密度
1.539

折射率
1.4700

灵敏度
Keep Cold. Moisture Sensitive.

溶解性
Soluble in Ether, Benzene, Chloroform, Ethanol. Insoluble in water.

Beilstein
970619

GHS危害和防范说明

GHS符号

Hazard Statements
H301-H330-H314-H318
Toxic if swallowed.Fatal if inhaled.Causes severe skin burns and eye damage.Causes serious eye damage.

Precautionary Statements
P301+P310a-P303+P361+P353-P304+P340-P305+P351+P338-P320-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment is urgent (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
II

危险类别
22-23-34
Harmful if swallowed.Toxic by inhalation.Causes burns.

安全等级
9-20-26-36/37/39-45
Keep container in a well-ventilated place.When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

TSCA
是