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Retigabine

瑞替加滨

品牌
Supelco
CAS
150812-12-7
货号
90221
规格纯度
analytical standard
参考价格
2223.16 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Retigabine is an antiepileptic drug, which activates neuronal KCNQ-type K+ channels by inducing a large hyperpolarizing shift of steady-state activation.

应用

Retigabine may be used as a reference standard in the determination of retigabine in biological matrices using high-performance liquid chromatography coupled with tandem mass spectrometry with positive ion atmospheric pressure chemical ionization (HPLC-APCI-MS/MS).

生化/生理作用

Retigabine (Ezogabine) is a Kv7.2-7.5 (KCNQ2-5) neuronal potassium channel opener witrh anticonvulsant activity.

基本信息

经验(实验)分子式C16H18FN3O2
分子量303.33
Beilstein8072099
MDL编号MFCD04307735
PubChem化学物质编号329769861
NACRESNA.24

产品性质

质量水平100
等级analytical standard
测定≥98.0% (HPLC)
保质期limited shelf life, expiry date on the label
drug controlUSDEA Schedule IV
technique(s)HPLC: suitable
gas chromatography (GC): suitable
杂质≤1.0% water (calc. from elemental analysis)
application(s)forensics and toxicology
veterinary
格式neat
储存温度2-8℃
SMILES stringFC1=CC=C(CNC2=CC(N)=C(NC(OCC)=O)C=C2)C=C1
InChI1S/C16H18FN3O2/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11/h3-9,19H,2,10,18H2,1H3,(H,20,21)
InChI keyPCOBBVZJEWWZFR-UHFFFAOYSA-N
Gene Informationhuman ... KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479)

安全信息

象形图GHS06GHS09
警示用语:Danger
危险声明H301 + H331 - H410
预防措施声明P261 - P264 - P270 - P273 - P301 + P310 - P304 + P340 + P311
危险分类Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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