产品说明
一般描述
Metoclopramide is typically employed as an antiemetic drug or a gastrointestinal prokinetic drug in adults and children.
Metoclopramide is a drug, which can be effective in the treatment of severe nausea and vomiting caused by the anticancer drug cis-platinum.
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Metoclopramide may be used as a reference standard for the determination of the analyte in serum samples using reversed-phase high-performance liquid chromatography (RP-HPLC) with electrochemical detection.
Metoclopramide may be used as an analytical reference standard for the determination of the analyte in:
- Human plasma by liquid–liquid extraction (LLE) with dichloromethane followed by hydrophilic interaction chromatography-electrospray iionization-tandem mass spectrometry (HILIC-ESI-MS/MS) operating in selected reaction monitoring (SRM) mode of detection.
It may also be used as an internal standard for the determination of loratadine and desloratadine in:
- Human plasma by high performance liquid chromatography (HPLC) coupled to MS/MS with multiple reaction monitoring (MRM) detection.
法律信息
VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH
基本信息
| 经验(实验)分子式 | C14H22ClN3O2 |
| 分子量 | 299.80 |
| Beilstein | 1884366 |
| EC 号 | 206-662-9 |
| MDL编号 | MFCD00211338 |
| PubChem化学物质编号 | 329754232 |
| NACRES | NA.24 |
产品性质
| 质量水平 | 100 |
| 等级 | analytical standard |
| 产品线 | VETRANAL® |
| 保质期 | limited shelf life, expiry date on the label |
| technique(s) | HPLC: suitable gas chromatography (GC): suitable |
| application(s) | forensics and toxicology pharmaceutical (small molecule) |
| 格式 | neat |
| 储存温度 | 2-8℃ |
| SMILES string | CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC |
| InChI | 1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) |
| InChI key | TTWJBBZEZQICBI-UHFFFAOYSA-N |
| Gene Information | human ... DRD2(1813), HTR3A(3359), HTR4(3360) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 预防措施声明 | P264 - P270 - P301 + P312 - P501 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
