产品说明
一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
生化/生理作用
1-甲基烟酰胺 (MNA) 是烟酰胺的初级代谢产物，主要由烟酰胺 N-甲基转移酶 (NNMT) 生成。1-甲基烟酰胺 (MNA) 具有抗血栓和抗炎作用。最近的一项研究表明，MNA 可能通过直接作用于内皮发挥抗血栓和抗炎作用，通过提高 NO 生物利用度和减少 eNOS 依赖性氧化应激发挥血管舒张作用。NNMT 活性增强是多种类型癌症的特征。MNA 在与 NNMT 的超表达联系的肿瘤发生中有多少直接参与正在调查中。在不产生 NNMT 的 SH-SY5Y 神经母细胞瘤细胞中，MNA 本身增加了线粒体复合物 I 的活性并增加了癌细胞的活力。
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAB9787 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
基本信息
| 经验(实验)分子式 | C7H9ClN2O |
| 分子量 | 172.61 |
产品性质
| 等级 | certified reference material pharmaceutical secondary standard |
| 形式 | powder |
| 包装 | pkg of 100 mg |
| 储存温度 | 2-30℃ |
| InChI | 1S/C7H8N2O.ClH/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H |
| InChI key | BWVDQVQUNNBTLK-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
