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Fingolimod Hydrochloride

2-氨基-2- [2-(4-辛基-苯基)-乙基]-丙烷-1,3-二醇 盐酸盐

品牌
Supelco
CAS
162359-56-0
货号
PHR2790
包装型号
规格纯度
参考价格
12717 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

生化/生理作用

FTY720是一种免疫调节药物以及1-磷酸鞘氨醇(S1P)受体的调节剂。 鞘氨醇激酶对FTY270的磷酸化可导致S1P1R的内化,从而螯合淋巴结中的淋巴细胞,阻止它们参与自身免疫反应。 临床上,它已被批准用于治疗多发性硬化症(MS)。研究显示其可通过抑制S1PR阻断和逆转紫杉醇诱导的化疗诱导的周围神经病变(CIPN),并可抑制小鼠脑海马中组蛋白脱乙酰酶的活性,从而调节记忆。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC6340 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C19H33NO2 · HCl
分子量343.93

产品性质

等级certified reference material
pharmaceutical secondary standard
描述Pharmaceutical Secondary Standard; Certified Reference Material
形式powder
包装pkg of 500 mg
药典可追溯性traceable to PhEur Y0002055
traceable to USP 1270480
储存温度2-30℃
InChI1S/C19H33NO2.ClH/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22;/h9-12,21-22H,2-8,13-16,20H2,1H3;1H
InChI keySWZTYAVBMYWFGS-UHFFFAOYSA-N

安全信息

象形图GHS08
警示用语:Warning
危险声明H373
预防措施声明P260 - P314 - P501
危险分类STOT RE 2
靶器官Immune system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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