产品说明
一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
生化/生理作用
一种铁螯合剂，常用于研究细胞增殖和凋亡。 体外 和 体内 实验均显示其对血管平滑肌细胞具有抗增殖作用，并抑制G1期细胞的增殖。 据报道，它也诱导p53。 通过螯合铁诱导HL-60细胞凋亡。 经过1μM去铁胺处理48小时后，DNA明显断裂。 细胞经1μM去铁胺处理仅24小时后发生凋亡;48小时后观察到核坍塌。 一些研究表明，它具有抗氧化性能，并保护细胞免受H2O2诱导的损伤。
分析说明
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
基本信息
| 经验(实验)分子式 | C25H48N6O8 · CH4O3S |
| 分子量 | 656.79 |
| MDL编号 | MFCD00058605 |
产品性质
| 质量水平 | 300 |
| 等级 | certified reference material pharmaceutical secondary standard |
| CofA | current certificate can be downloaded |
| 包装 | pkg of 500 mg |
| application(s) | pharmaceutical |
| SMILES string | CS(O)(=O)=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN |
| InChI | 1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4) |
| InChI key | IDDIJAWJANBQLJ-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
