产品说明
一般描述
Bergamottin, a member of the furanocoumarin family, is primarily found in grapefruit juice. It is reported to be a novel signal transducer and activator of the transcription 3 (STAT3) inhibitor. It is a known drug inhibitor of cytochrome P450 34A and also exhibits diverse anti-tumor and anti-inflammatory activities.
应用
Bergamottin may be used as an analytical standard to test its efficacy in the following:
- Blocker of STAT3 activation pathway in tumor cells; its potential in the therapy of multiple myeloma (MM) and other cancers is investigated.
- Prevention and the treatment of cancer via suppression of the NF-kB signaling pathway and its regulated gene products.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
基本信息
经验(实验)分子式 | C21H22O4 |
分子量 | 338.40 |
Beilstein | 1353914 |
MDL编号 | MFCD00017409 |
PubChem化学物质编号 | 329747253 |
NACRES | NA.24 |
产品性质
等级 | analytical standard |
质量水平 | 100 |
测定 | ≥98.0% (HPLC) |
technique(s) | HPLC: suitable gas chromatography (GC): suitable |
mp | 75-80 ℃ |
application(s) | food and beverages |
格式 | neat |
储存温度 | 2-8℃ |
SMILES string | C\C(C)=C\CC\C(C)=C\COc1c2C=CC(=O)Oc2cc3occc13 |
InChI | 1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-16-7-8-20(22)25-19(16)13-18-17(21)10-12-23-18/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+ |
InChI key | DBMJZOMNXBSRED-OQLLNIDSSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |