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Famciclovir

泛昔洛韦

品牌
Supelco
CAS
104227-87-4
货号
PHR1696
规格纯度
Pharmaceutical Secondary Standard; Certified Reference Material
参考价格
2191.84 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Famciclovir is an antiviral drug, which is predominantly used in the treatment of herpes virus infection. It is an inactive prodrug, which on administration, undergoes rapid biotransformation to penciclovir.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Famciclovir may be used as a reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by spectrophotometry and high performance liquid chromatography.

生化/生理作用

泛昔洛韦是一种抗逆转录病毒鸟苷类似物,用于治疗疱疹病毒感染和乙肝。泛昔洛韦可迅速转化为喷昔洛韦。病毒胸苷激酶将喷昔洛韦磷酸化为单磷酸形式,然后细胞激酶又将其转换为三磷酸喷昔洛韦。喷昔洛韦三磷酸可竞争性抑制病毒 DNA 聚合酶,从而抑制病毒复制。长时间服用会形成耐药性;这通常表现为筛选出了一批 DNA 聚合酶基因逆转录酶结构域突变的预先存在的耐药性菌株。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3254 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C14H19N5O4
分子量321.33
MDL编号MFCD00866964
PubChem化学物质编号329823560
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1269152
储存温度2-8℃
SMILES stringCC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O
InChI1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)
InChI keyGGXKWVWZWMLJEH-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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