产品说明
一般描述
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Chlorpropamide belongs to the sulfonylurea class of drugs and is found to be clinically effective in the treatment of Diabetes mellitus (DM). Its mode of action involves the stimulation of insulin release from the β-cells of the pancreas in response to a glucose load. It helps in increasing the number of insulin receptors, thereby enhancing the effect of insulin on the liver and promotes peripheral glucose utilization.
应用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Chlorpropamide may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using capillary zone elctrophoresis technique and spectrophotometric technique.
分析说明
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
附注
To see an example of a Certificate of Analysis for this material enter LRAA0019 in the slot below. This is an example certificate only and may not be the lot that you receive.
基本信息
经验(实验)分子式 | C10H13ClN2O3S |
分子量 | 276.74 |
EC 号 | 202-314-5 |
MDL编号 | MFCD00079004 |
PubChem化学物质编号 | 329823279 |
NACRES | NA.24 |
产品性质
质量水平 | 300 |
等级 | certified reference material pharmaceutical secondary standard |
CofA | current certificate can be downloaded |
technique(s) | HPLC: suitable gas chromatography (GC): suitable |
application(s) | pharmaceutical (small molecule) |
格式 | neat |
药典可追溯性 | traceable to PhEur C1905000 traceable to USP 1126009 |
储存温度 | 2-30℃ |
SMILES string | CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 |
InChI | 1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14) |
InChI key | RKWGIWYCVPQPMF-UHFFFAOYSA-N |
Gene Information | human ... ABCC8(6833), KCNJ11(3767) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H361f - H373 |
预防措施声明 | P201 - P301 + P312 + P330 - P308 + P313 |
危险分类 | Acute Tox. 4 Oral - Repr. 2 - STOT RE 2 |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |