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(±)-Miconazole nitrate salt

(±)-咪康唑 硝酸盐

品牌
Supelco
CAS
22832-87-7
货号
PHR1163
规格纯度
Pharmaceutical Secondary Standard; Certified Reference Material
参考价格
827.53 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Miconazole nitrate is an imidazole derivative and a broad spectrum antifungal drug used in the management of fungal outbreak in humans and veterinary animals.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Miconazole nitrate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various techniques.

生化/生理作用

咪康唑与 14-α 相互作用脱甲基酶,一种麦角固醇生物合成所必需的细胞色素 P-450 酶。麦角固醇的抑制导致细胞通透性增加引起细胞内容物渗漏。咪康唑还可能抑制内源性呼吸,与细胞膜中的磷脂相互作用,抑制酵母菌转化为菌丝形式,抑制嘌呤摄取,干扰甘油三酯和磷脂的生物合成。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

Values of analytes vary lot to lot.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3325 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C18H14Cl4N2O · HNO3
分子量479.14
EC 号245-256-6
MDL编号MFCD00058161
PubChem化学物质编号329823180
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 253
traceable to PhEur M1900000
traceable to USP 1443500
储存温度2-30℃
SMILES stringClC1=CC(Cl)=CC=C1C(OCC2=CC=C(Cl)C=C2Cl)CN3C=CN=C3.[O-][N+](O)=O
InChI1S/C18H14Cl4N2O.HNO3/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22;2-1(3)4/h1-8,11,18H,9-10H2;(H,2,3,4)
InChI keyMCCACAIVAXEFAL-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H317
预防措施声明P280 - P301 + P312 + P330 - P302 + P352
危险分类Acute Tox. 4 Oral - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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