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Amitriptyline Hydrochloride

盐酸阿米替林

品牌
Supelco
CAS
549-18-8
货号
PHR1384
规格纯度
Pharmaceutical Secondary Standard; Certified Reference Material
参考价格
1359.83 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Amitriptyline hydrochloride is a drug, and a tricyclic antidepressant with anticholinergic activity. It is widely used in combination with chlordiazepoxide 7-chloro-2-(methyl-amino)-5-phenyl-3H-1,4-benzodiazepine-4-oxide for the treatment of patients with moderate to severe depression associated with moderate to severe anxiety.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Amitriptyline hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique and reversed-phase high-performance liquid chromatography.

生化/生理作用

三环抗抑郁剂;抑制分别具有 100nM 和 14.7nM Kis 的去甲肾上腺素和 5-羟色胺转运蛋白;对 α1-肾上腺素受体、5-羟色胺和毒蕈碱型乙酰胆碱受体具有高度的体外亲和力。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA1640 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C20H23N · HCl
分子量313.86
EC 号208-964-6
MDL编号MFCD00012537
PubChem化学物质编号329823361
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 16
traceable to PhEur Y0000563
traceable to USP 1029002
储存温度2-30℃
SMILES stringCl[H].CN(C)CC\C=C1\c2ccccc2CCc3ccccc13
InChI1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H
InChI keyKFYRPLNVJVHZGT-UHFFFAOYSA-N
Gene Informationhuman ... SLC6A2(6530), SLC6A4(6532)

安全信息

象形图GHS06GHS08GHS09
警示用语:Danger
危险声明H301 - H319 - H361d - H410
预防措施声明P201 - P273 - P301 + P310 + P330 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 2
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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