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Letrozole

来曲唑

品牌
Supelco
CAS
112809-51-5
货号
PHR1540
规格纯度
Pharmaceutical Secondary Standard; Certified Reference Material
参考价格
1596.92 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Letrozole is used for the treatment of breast cancer in hormone-dependent postmenopausal patients. The drug works by blocking the synthesis of estrogen, a causative agent for cancer.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Letrozole may be used as a pharmaceutical reference standard for the determination of the analyte in biological/environmental samples and pharmaceutical formulations by various chromatography techniques.

生化/生理作用

来曲唑是第三代非甾体芳香酶抑制剂。 它是芳香酶系统的竞争性抑制剂,因此可抑制雄激素向雌激素转化。来曲唑通过竞争性结合到该酶的细胞色素P450亚基的血红素上而抑制芳香酶,导致所有组织中雌激素的生物合成减少。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA4186 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C17H11N5
分子量285.30
MDL编号MFCD00866241
PubChem化学物质编号329823451
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to PhEur Y0000685
traceable to USP 1356971
储存温度2-30℃
SMILES stringN#CC(C=C1)=CC=C1C(N2C=NC=N2)C3=CC=C(C#N)C=C3
InChI1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
InChI keyHPJKCIUCZWXJDR-UHFFFAOYSA-N
Gene Informationhuman ... CYP19A1(1588)

安全信息

象形图GHS08
警示用语:Warning
危险声明H361fd - H373
预防措施声明P202 - P260 - P280 - P308 + P313 - P405 - P501
危险分类Repr. 2 - STOT RE 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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