Technical Notes:

In many respects the catalytic profile of the Me( BIPHEP ligands is similar to that of other atro binap and its many analogs. The nature of the PR2 group strongly influences the c atalytic perf ormar rhodium and ruthenium MeO-BIPHEP catalysts are highly effective for the hydrogenation of various several synthetically useful c-c coupling reactions.

1. See 15-0042.

2.Ru and Ir catalyzed dynamic kinetic resolution for the synthesis of hydroxy, amino acid derivatives .

3. Ru-catalyzed asymmetric hydrogenation of ketones and alkenes .

4.Ir catalyzed enantioselective hydrogenation of heteroaromatic compounds .

5.Conjugate addition using 2-heteroaryl titanates and zinc reagents .

6.Enantio- and regios elective heck-type reaction of aryl boronic acids with 2,3-dihydrofuran

7.Rhodium- catalyzed carbonyl Z-dienylation.

8. Rhodium-catalyzed as ymmetric 1 ,4 addition of arylboronic acids to maleimides and enones .