Technical Note:
1. A chiral fluorous support for conventional and high-throughput organic synthesis. Induces high stereos electivity in aldol reactions, cycloadditions, conjugate additions and a variety of other reactions of N acyl derivatives. The fluorous chain permits rapid and efficient isolation of products by solid phase extraction, using only minimal amounts of common solvents.Class of catalytic ligands which when used with a reducing agent, exhibit enantioselectivity in the reduction of a wide range of substrates.
References:
J. Org, Chem.. 2005, 70, 9940.
2. Org. Lett., 2005, 7, 2755.