产品说明
一般描述
Zinc finger protein 282/ubiquitin-like protein modifier (ZNF282, HUB1), a ubiquitin-like protein, promotes alternative splicing of SRC1 pre-mRNA. HUB1 is essential for subcellular targeting of Snu66, a component of the U4/U6.U5 tri-snRNP splicing complex.
特异性
Anti-ZNF282 (AB1) polyclonal antibody reacts with canine, bovine, human, mouse, and rat zinc finger protein 282/ubiquitin-like protein modifier proteins.
免疫原
Synthetic peptide directed towards the N terminal region of human ZNF282
应用
Anti-ZNF282 (AB1) polyclonal antibody is used to tag zinc finger protein 282/ubiquitin-like protein modifier for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of zinc finger protein 282/ubiquitin-like protein modifier in the regulation of pre-mRNA splicing.
生化/生理作用
ZNF282 contains 1 KRAB domain and 5 C2H2-type zinc fingers. It belongs to the krueppel C2H2-type zinc-finger protein family and binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat.
序列
Synthetic peptide located within the following region: QQLGIQGLGLDSGSWSWAQALPPEEVCHQEPALRGEMAEGMPPMQAQEWD
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 74 kDa |
| species reactivity | rabbit, human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_003566 |
| UniProt登记号 | Q9UDV7 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ZNF282(8427) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
