产品说明
一般描述
ZNF274 is a Kruppel-type zinc-finger protein that functions as a transcriptional repressor in nucleoli. This protein can carry histone methyltransferase SETDB1 to the 3′ end of the ZNF gene.
Rabbit Anti-ZNF274 antibody recognizes bovine, canine, human, mouse, and rat ZNF274.
免疫原
Synthetic peptide directed towards the N terminal region of human ZNF274
应用
Rabbit Anti-ZNF274 antibody can be used for western blot (2.5μg/ml) and IHC (4-8μg/ml, using paraffin-embedded tissues) applications.
生化/生理作用
ZNF274 is a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus.This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.
序列
Synthetic peptide located within the following region: YPELQLDPKLDPLPAESPLMNIEVVEVLTLNQEVAGPRNAQIQALYAEDG
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 62 kDa |
| species reactivity | human, rabbit |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_057408 |
| UniProt登记号 | Q96GC6-3 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ZNF274(10782) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
