产品说明
一般描述
The gene TRIM68 (tripartite motif containing 68) belongs to the tripartite motif-containing protein (TRIM) family, the members of which contain a RING (really interesting new gene) finger, a B-box and a coiled-coil motif. Additionally, trim68 contains a carboxy-terminal PRY/SPRY (splA kinase and ryanodine receptors) domain. The gene is mapped to human chromosome 11p15.4.
免疫原
Synthetic peptide directed towards the C terminal region of human TRIM68
生化/生理作用
The members of TRIM (tripartite motif-containing protein) family of proteins participate in several biological processes. Alteration in their expression is associated with genetic diseases, viral infection, and cancer development. TRIM68 (tripartite motif containing 68) interacts with androgen receptor (AR) and serves as its co-activator. It possesses ubiquitin ligase activity and may function in AR-dependent transcription. It has been found to be associated with Sjögren′s syndrome and serves as a diagnostic marker. Trim68 is highly expressed in prostate and may be involved in carcinogenesis.
序列
Synthetic peptide located within the following region: RLRKGNEYRAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHI
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 56 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_060543 |
| UniProt登记号 | Q96PF7 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TRIM68(55128) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
