产品说明
一般描述
TLR6 is a member of the toll-like receptor family and activates NF-κB and c-Jun N-terminal kinase (JNK). TLR6 polymorphisms have been linked to the risk of invasive aspergillosis.
Rabbit Anti-TLR6 antibody recognizes human TLR6.
免疫原
Synthetic peptide directed towards the middle region of human TLR6
应用
Rabbit Anti-TLR6 antibody can be used for western blot (1.0μg/ml) and immunohistochemical (4-8μg/ml, using paraffin embedded tissues) assays.
生化/生理作用
TLR6 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins.
序列
Synthetic peptide located within the following region: KCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHIT
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD03456043 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 53 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_006059 |
| UniProt登记号 | Q2NKL3 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TLR6(10333) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
