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Anti-TIPIN (AB2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV50620
规格纯度
IgG fraction of antiserum
参考价格
3311.54 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

TIPIN forms a complex with TIMELESS and regulates the stabilization of replication forks. This complex facilitates the cohesion of sister chromatids. It is also involved in Chk1 phosphorylation by ATR during genotoxic stress response.
Rabbit Anti-TIPIN antibody recognizes human, mouse, rat, bovine, zebrafish, chicken, and canine TIPIN.

免疫原

Synthetic peptide directed towards the N terminal region of human TIPIN

应用

Rabbit Anti-TIPIN antibody is suitable for western blot at a concentration of 5 μg/ml.

生化/生理作用

TIPIN is required for normal progression of S-phase. It is important for cell survival after DNA damage or replication stress and may be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.

序列

Synthetic peptide located within the following region: MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGA

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 34 kDa
species reactivityhuman, bovine, mouse, guinea pig, horse, rabbit
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_060328
UniProt登记号Q9BVW5
运输wet ice
储存温度−20℃
Gene Informationhuman ... TIPIN(54962)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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