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Anti-Tiparp (N-term) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1300963
规格纯度
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
参考价格
4618.16 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The gene TIPARP (TCDD-inducible poly [ADP-ribose] polymerase) is mapped to human chromosome 3q25. It belongs to the poly [ADP-ribose] polymerase (PARP) family. The protein has a PARP catalytic domain, a WWE (tryptophan-tryptophan-glutamate) protein interaction domain and a CCCH-type zinc-finger domain. It is expressed in variety of tissues, including liver, heart, spleen, brain and reproductive organs.

免疫原

TIPARP (NP_849223, 65-100)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of mouse TIPARP.

生化/生理作用

TIPARP (TCDD-inducible poly [ADP-ribose] polymerase) is controlled by the aryl hydrocarbon receptor (AHR). It is a mono-ADP-ribosyltransferase and works as a transcriptional repressor of AHR. It is required for the transfer of ADP-ribose onto target proteins using NAD+. The environmental toxin 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin, dioxin (TCDD) increases the expression of this gene. It participates in the inhibition of hepatic gluconeogenesis mediated by TCDD.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式saturated ammonium sulfate (SAS) precipitated
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
NCBI登记号NP_849223
UniProt登记号Q8C1B2
运输dry ice
储存温度−20℃
Gene Informationhuman ... TIPARP(25976)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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