产品说明
一般描述
THO complex 1 (THOC1, HPR1, P84, P84N5) is a component of the TREX (transcription/export) complex that physically couples elongating RNA polymerase II with RNA processing and nuclear RNA export factors to regulate gene expression. THOC1 is required for embryonic development at the time of implantation. THOC1 may be involved in neoplastic transformation.
特异性
Anti-THOC1 polyclonal antibody reacts with bovine, canine, human, mouse, and rat THO complex 1 proteins.
免疫原
Synthetic peptide directed towards the C terminal region of human THOC1
应用
Anti-THOC1 polyclonal antibody is used to tag THO complex 1 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of THO complex 1 in TREX complex function and gene expression.
生化/生理作用
THOC1 is part of the TREX (transcription/export) complex, which includes TEX1, THO2, ALY, and UAP56.HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
序列
Synthetic peptide located within the following region: TNQQFKSLQEYLENMVIKLAKELPPPSEEIKTGEDEDEEDNDALLKENES
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 76 kDa |
| species reactivity | human, dog, bovine, horse, rabbit, guinea pig, mouse, rat |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_005122 |
| UniProt登记号 | Q96FV9 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... THOC1(9984) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
