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Anti-TFB2M (AB2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV39550
规格纯度
IgG fraction of antiserum
参考价格
3311.54 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

TFB2M is a mitochondrial transcription factor that regulates the expression of Serca2 gene in rat cardiomyocytes. It is also known to induce the transcription of human mtDNA.
Rabbit Anti-TFB2M (AB1) antibody recognizes human TFB2M.

免疫原

Synthetic peptide directed towards the C terminal region of human TFB2M

应用

Rabbit Anti-TFB2M antibody is suitable for western blot applications at a concentration of 5 μg/ml.

生化/生理作用

TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

序列

Synthetic peptide located within the following region: ATVIDHLRSLTPLDARDILMQIGKQEDEKVVNMHPQDFKTLFETIERSKD

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 45 kDa
species reactivityhuman
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_071761
UniProt登记号Q9H5Q4
运输wet ice
储存温度−20℃
Gene Informationhuman ... TFB2M(64216)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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