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Anti-TCF2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV32320
规格纯度
affinity isolated antibody
参考价格
6305.78 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

TCF2 is a homeodomain transcription factor that regulates renal development in embryos. Variations in TCF2 have been implicated in fetal hyperechogenic kidneys and protection against diabetes type 2.
Rabbit Anti-TCF2 antibody recognizes canine, pig, chicken, zebrafish, human, mouse, and rat TCF2.

免疫原

Synthetic peptide directed towards the N terminal region of human HNF1B

应用

Rabbit Anti-TCF2 antibody can be used for western blot applications at a concentration of 0.2μg/ml.

生化/生理作用

Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.

序列

Synthetic peptide located within the following region: LETLPLSPGSGAEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPIL

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 45 kDa
species reactivitymouse, bovine, rat, guinea pig, horse, dog, human
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_000449
UniProt登记号P35680
运输wet ice
储存温度−20℃
Gene Informationhuman ... TCF2(6928)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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