产品说明
一般描述
IGSF8/PGRL/EWI-2 is a membrane protein that contains 4 Ig domains and forms highly proximal, specific and stoichiometric complexes with both CD9 and CD81 a tetraspanin. Tetraspanins and their molecular partners from primary complexes that then undergo tetraspanin-tetraspanin interactions to form a network of molecular interactions call a tetraspanin web. IGSF8 then may play a key role in diverse functions ascribed to CD81 and CD9 including oocyte fertilization or hepatitis C virus function, regulation of proliferation and differentiation of keratinocytes. It may also be a negative regulator of cell motility and suppress T-cell mobility coordinately with CD81.
免疫原
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human TBXA2R. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Dog, Panda (95%); Elephant (90%); Bat, Bovine, Pig (85%); Opossum (80%).
特点和优势
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外形
Supplied at 1 mg/ml
Solution in phosphate-buffered saline containing less than 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: 4 μg/mL |
| UniProt登记号 | P21731 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TBXA2R(6915) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
