产品说明
一般描述
Afadin- and α-actinin-binding protein is encoded by the SSX2IP gene in humans. The gene encodes a protein that binds to the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. It is associated with the cytoplasmic tail of nectin which is a Ca2+-independent immunoglobulin-like cell-cell adhesion molecule.
免疫原
Synthetic peptide directed towards the middle region of human SSX2IP
应用
Anti-SSX2IP antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/mL.
生化/生理作用
Afadin- and α-actinin-binding protein localizes at cell-cell adherens junctions (AJs). It acts as novel centrosome maturation factor and also as a maintenance factor during the onset of vertebrate development. It preserves centrosome integrity and mitosis during the rapid cleavage division of blastomeres in somatic cells. SSX2IP also promotes the development and metastasis of hepatocellular carcinoma and contributes to the drug resistance of hepatoma cells.
序列
Synthetic peptide located within the following region: KVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATA
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 68 kDa |
| species reactivity | horse, bovine, rabbit, rat, dog, human, guinea pig |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_054740 |
| UniProt登记号 | Q9Y2D8 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SSX2IP(117178) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
