产品说明
一般描述
SNF1-like kinase (SNF1LK, MSK, SIK), a class II HDAC kinase, promotes survival of skeletal myocytes and may function in cell cycle regulation at the level of G2/M transition.
特异性
Anti-SNF1LK polyclonal antibody reacts with bovine, human, mouse, rat, chicken, and canine SNF1-like kinases.
免疫原
Synthetic peptide directed towards the N terminal region of human SNF1LK
应用
Anti-SNF1LK polyclonal antibody is used to tag SNF1-like kinase for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of SNF1-like kinase in cell survival and cell cycle regulation.
生化/生理作用
SNF1LK play a transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. It also plays a potential role in G2/M cell cycle regulation. It inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.
序列
Synthetic peptide located within the following region: MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTK
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 85 kDa |
| species reactivity | horse, bovine, human, rat, pig |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_775490 |
| UniProt登记号 | P57059 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SNF1LK(150094) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
