产品说明
一般描述
RNF36 (TRIM69) is a tripartite motif containing protein that associates with promyelocytic leukemia (PML) protein and induces cell death/apoptosis. RNF36 is also known to function as an E3 ubiquitin ligase in human testis and may be involved in ubiquitination during spermatogenesis.
Rabbit Anti-RNF36 antibody recognizes human, mouse, rat, and bovine RNF36.
免疫原
Synthetic peptide directed towards the N terminal region of human RNF36
应用
Rabbit Anti-RNF36 antibody is suitable for western blot applications at a concentration of 2.0 μg/ml.
生化/生理作用
RNF36 is specifically expressed in germ cells at round spermatid stages during spermatogenesis. The protein encoded by this gene contains an N-terminal RING finger motif, a B-box, and a C-terminal B-30.2-like domain. When overexpressed in COS-7 and HEK-293 cells, this protein was shown to induce cell apoptosis.
序列
Synthetic peptide located within the following region: SIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGP
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 41 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_542783 |
| UniProt登记号 | Q8IYY3 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... RNF36(140691) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
