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Anti-PHB2 (AB2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV48315
规格纯度
affinity isolated antibody
参考价格
6250.82 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

PHB2 codes for prohibitin 2 that protects the cohesion of sister chromatids during mitosis. PHB2 downregulation has been linked to anorexia-induced fission and apoptosis in mitochondria.
Rabbit Anti-PHB2 antibody recognizes bovine, chicken, human, mouse, rat, and canine PHB2.

免疫原

Synthetic peptide directed towards the N terminal region of human PHB2

应用

Rabbit Anti-PHB2 (AB2) antibody is suitable for western blot applications at a concentration of 1μg/ml.

生化/生理作用

PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.

序列

Synthetic peptide located within the following region: WFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQR

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 33 kDa
species reactivityhorse, mouse, rabbit, rat, bovine, human, dog, guinea pig
浓度0.5 mg - 1 mg/mL
technique(s)immunohistochemistry: suitable
western blot: suitable
NCBI登记号NP_001138303
UniProt登记号Q99623
运输wet ice
储存温度−20℃
Gene Informationhuman ... PHB2(11331)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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