产品说明
一般描述
PDLIM5 (PDZ and LIM domain 5) is a LIM domain containing protein consisting of an N-terminal PDZ (post-synaptic density-95/discs large/zone occludens-1) domain and three C-terminal LIM (Lin-11 Isl-1 mec03) domains. It is ubiquitously expressed in the brain. Cysteine-rich LIM domains are double zinc fingers type, which participates in the protein-protein interactions.
免疫原
Synthetic peptide directed towards the C terminal region of human PDLIM5
应用
Anti-PDLIM5 (AB2) antibody produced in rabbit is suitable for western blot applications.
生化/生理作用
PDLIM5 protein belongs to a family of scaffold proteins characterized by the presence of a PDZ domain at the N terminus and 1-3 LIM domains at the C terminus. PDLIM5 localizes protein kinases to the Z-disk in striated muscles and regulates the expansion of cardiomyocytes. It negatively regulates postsynaptic excitatory synapses and is a candidate gene for bipolar disorders.
序列
Synthetic peptide located within the following region: AGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSVNF
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 64 kDa |
| species reactivity | dog, bovine, rat, horse, human, guinea pig, mouse, rabbit |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_006448 |
| UniProt登记号 | Q5UW38 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PDLIM5(10611) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
