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Anti-KCNN1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV35095
规格纯度
IgG fraction of antiserum
参考价格
3311.54 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

KCNN1 (SK1) codes for a voltage-independent, calcium-activated channel integral membrane protein. This protein belongs to potassium channel family. Mouse SK1 protein can interact with calmodulin without the aid of Ca2+ ions.
Rabbit Anti-KCNN1 antibody recognizes human and bovine KCNN1.

免疫原

Synthetic peptide directed towards the C terminal region of human KCNN1

应用

Rabbit Anti-KCNN1 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml.

生化/生理作用

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN1 is a member of the KCNN family of potassium channels.

序列

Synthetic peptide located within the following region: KIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLD

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD06798511

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 60 kDa
species reactivityhuman
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_002239
UniProt登记号Q6DJU4
运输wet ice
储存温度−20℃
Gene Informationhuman ... KCNN1(3780)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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