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Anti-ITM2C antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2106682
规格纯度
affinity isolated antibody
参考价格
6193.36 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

The immunogen for anti-ITM2C antibody: synthetic peptide derected towards the middle region of human ITM2C

生化/生理作用

ITM2C is a negative regulator of beta amyloid peptide production. ITM2C may inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor.ITM2C may play a role in TNF-induced cell death and neuronal differentiation.

序列

Synthetic peptide located within the following region: EDSLSSQVRTQMELEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQR

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 30 kDa
species reactivityguinea pig, rat, horse, mouse, dog, sheep, bovine, human
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NM_030926
UniProt登记号Q9NQX7
运输wet ice
储存温度−20℃
Gene Informationhuman ... ITM2C(81618)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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