产品说明
一般描述
HOXB6 belongs to the HOX family of homeobox protein that regulate hematopoiesis. Overexpression of HOXB6 has been linked to acute myeloid leukemia. Furthermore, HOXB6 is known to interact with CREB-binding protein (CBP) and repress globin expression.
Rabbit Anti-HOXB6 antibody recognizes human, mouse, rat, canine, and bovine HOXB6.
免疫原
Synthetic peptide directed towards the N terminal region of human HOXB6
应用
Rabbit Anti-HOXB6 antibody can be used for western blot (1μg/ml) applications.
生化/生理作用
HOXB6 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.
序列
Synthetic peptide located within the following region: ALSGADEQPPFHPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMNSCN
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 25 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_061825 |
| UniProt登记号 | P17509 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... HOXB6(3216) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
