产品说明
免疫原
Synthetic peptide directed towards the C terminal region of human GPAA1
应用
Anti-GPAA1 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5μg/ml. It is also useful for immunohistochemistry at a concentration of 4-8μg/ml.
生化/生理作用
GPAA1 [glycosylphosphatidylinositol anchor attachment 1 homolog (yeast)] gene also referred to as GAA1 or hGAA1 encodes a protein which is a component of a transamidase. It is located at 8q24.3 and contains twelve exons that span about 4kb. It plays a pivotal role in GPI anchoring at the GPI transfer step where it catalyzes the attachment of GPI to proteins containing a C-terminal GPR attachment signal. GPAA1 gene amplification results in overexpression of RNA and protein in hepatocellular carcinoma (HCC). Hence, it facilitates as a potential amplification target and regulates the behavior of tumor cells.
序列
Synthetic peptide located within the following region: LGSLFLWRELQEAPLSLAEGWQLFLAALAQGVLEHHTYGALLFPLLSLGL
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 67 kDa |
| species reactivity | bovine, human, rat, guinea pig, horse |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_003792 |
| UniProt登记号 | O43292 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... GPAA1(8733) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
